Fangfang Shi1, Chen Xia2, Jun Zhang2, Chuyong Chen2, Qi Chen2

1Department of Hematology, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, China
2Department of Orthopedics, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, China

Keywords: Degenerative scoliosis, posterior correction, quality of life, spinopelvic parameter, therapeutic effect.

Abstract

Objectives: This study aimed to investigate the correlations of spinopelvic parameters with the quality of life of patients with adult degenerative scoliosis (ADS) after posterior correction, and their relationships with efficacy

Patients and methods: Ninety patients (40 females, 50 males; mean age: 62.4±3.3 years; range, 47 to 73 years) with adult spinal deformity treated from March 2016 to May 2020 were retrospectively enrolled. The Scoliosis Research Society (SRS)-22 questionnaire was filled in by the patients, and the Oswestry disability index (ODI) and Visual Analog Scale (VAS) for back and lower limb pain were assessed. All the patients underwent posterior correction. Spearman’s analysis was conducted for the correlations of the spinopelvic sagittal parameters with quality of life. The risk factors for efficacy were identified using the multivariate logistic regression model to construct a nomogram model for efficacy and risk prediction.

Results: After the operation, significant reductions were detected in the sagittal vertical axis (SVA), pelvic tilt (PT), T1 pelvic angle (TPA), pelvic incidence minus lumbar lordosis (PI-LL), and the ODI score (p<0.05). The SVA and LL were significantly negatively correlated with all subitems on the SRS-22 questionnaire but positively correlated with VAS scores for back pain (p<0.05). Thoracic kyphosis was significantly positively correlated with self-image and mental status on the SRS-22 questionnaire (p<0.05), while TPA was negatively correlated with pain and self-image (p<0.05). The PI-LL was significantly negatively correlated with pain (p<0.05).

Conclusion: The SVA, LL, PT, and PI-LL were independent predictors of improvement in ODI after operation for ADS. The postoperative changes in spinopelvic parameters affected the clinical outcomes in patients with ADS.

Citation: Shi F, Xia C, Zhang J, Chen C, Chen Q. Correlations of spinopelvic parameters with quality of life of patients with adult degenerative scoliosis after posterior correction. Jt Dis Relat Surg 2024;35(3):554-561. doi: 10.52312/jdrs.2024.891.

Ethics Committee Approval

The study protocol was approved by the Zhejiang Provincial People’s Hospital Ethics Committee (date: 04.03.2016, no: ZRYLS2022102). The study was conducted in accordance with the principles of the Declaration of Helsinki.

Author Contributions

Designed this study and prepared this manuscript: F.S., C.X.; Collected and analyzed clinical data: J.Z., C.C.; Writing: Q.C. All authors approved the final version of this manuscript.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

This study was financially supported by the Health Science and Technology Plan Project of Zhejiang Province (No. 2022KY017).

Data Sharing Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.