The manuscript should be prepared in accordance with The Uniform Requirements for Manuscripts Submitted to Biomedical Journals - International Committee of Medical Journal Editors ( Manuscripts of randomized trials should comply with the CONSORT statement ( Observational studies should be reported in compliance with the STROBE statement (

Number pages consecutively beginning with the title page. Use double-spacing, Times New Roman font in pt. 12 size. Ensure the text is fully blinded and does not include any information on the authors and their institutions. Use continuous line numbers from the start of the manuscript, not starting afresh on each page.

Abbreviations should be defined at first mention and used consistently thereafter. Readers often find these confusing, so please use as few as possible.

Each part of the manuscript should begin on a new page in the following sequence:

  • Title page
  • Abstract
  • Main manuscript
  • Acknowledgments
  • References
  • Tables with titles
  • Figures and legends to figures.

Title Page: Title page should include the following:

  1. The title of the article should be concise; brief but comprehensive,
  2. a short title of at most 35 letters,
  3. full names, ORCID ID’s, e-mail addresses of each author with highest academic degrees and institutional affiliations,
  4. name(s) of the department(s) and institution(s),
  5. name, address, phone, mobile phone, and e-mail address of the author responsible for correspondence.

Title Page must be separate.

Abstract: An abstract of minimum 150 and maximum 300 words should be written. The abstract should state the purpose of the study, main findings and the principal conclusions in separate headings of: Objectives, Materials (Patients) and Methods, Results, and Conclusion. The abstract page should contain the title.

Keywords: Three to 6 keywords concordant with the National Library of Medicine (NLM) Medical Subject Headings (MeSH) vocabulary terms should be listed after the abstract.

Main manuscript: The text of the article should be divided into sections with the headings Introduction, Materials (Patients) and Methods, Results, Discussion, and Conclusion.

Introduction should state the purpose of the article and summarize the rationale for the study. Give only strictly pertinent references and limit this section to one page.

Materials (Patients) and Methods should describe the selection of the observational or experimental subjects clearly and in detail. Give references to established methods including statistics. Describe statistical methods in adequate detail. Statistical analysis must be performed in accordance with the guidelines on reporting statistics in medical journals (Altman DG, Gore SM, Gardner MJ, and Pocock SJ. Statistical Guidelines for Contributors to Medical Journals. Br Med J 1983; 7:1489-93). The software used for the analysis should be explicitly stated. For parametric tests, continuous variables are expressed in mean ± standard deviation, while for non-parametric tests; data are expressed in median and range (min- max) or median and interquartile range (25th and 75th percentiles). When complex analyses are used, the relative risk (RR), odds ratio (OR) and hazard ratio (HR) values are supported by providing confidence intervals (CI) and p values. Units should be prepared in accordance with the International System of Units (SI). Information on the patient consent, name of the ethics committee, and the ethics committee approval date and number (blinded) must be stated in the Patients and Methods section of the manuscript. An approval of research protocols by the Ethics Committee in accordance with international agreements (Helsinki Declaration, revised 2013, Guide for the Care and Use of Laboratory Animals - is required for experimental, clinical, and investigational drug studies, and some case reports. For research articles in humans or animals, approval by the institutional review board (IRB) and appropriate ethics committee are required. All articles studying human subjects must include a statement that the subjects gave informed consent to participate. For case reports and clinical pictures informed consent obtained from each patient and/or their families with the following statement is necessary; "The patients and/or their families were informed that data from the case would be submitted for publication and gave their consent.".

Results should be presented in logical sequence in the text, tables and illustrations. Data in the text should not be repeated in the tables or illustrations.

Discussion:? Emphasize the new and important aspects of the study without recapitulating the results. Relate the observations to other relevant studies. Limitations to the study should be presented. Present your conclusions in the Discussion section to provide recommendations on clinical application, and summary of the results and discussion. Conclusion should not be more than one or two sentences long.

Acknowledgements: List the individuals who contributed to the research, but are not an author here. Also, if present, include details about conflict of interest and financial disclosures in this section. Acknowledgements must be sent in a separate document.

References: Number references consecutively in the order in which they are first mentioned in the text, and they must be in the style used by PubMed/MEDLINE. Unpublished observations and personal communications should not be used. Use no more than 30 references unless necessary. References will strictly be controlled and the author may be asked to provide the full-text of any of the references. All authors should be listed if an article has six or less authors; if an article has more than six authors, first six authors are listed and the rest is represented by “et al.” Reference format and punctuation in the Text should be as in the following examples:

  • If the surname of the first author of the referenced article is given, “et al.” should be added after it, followed by its reference number within square brackets: “e.g. Brown et al. [1]”
  • Give references in the text using Arabic numerals in brackets: e.g. “[1]” (superscript preferred)
  • If more than one references are required in the main manuscript, references should be stated in a superscript square bracket with a comma at the end of the punctuation mark of the related sentence: e.g. [1,2,5]
  • If there are more than two consecutive references, the first and the last ones should be given with “-” mark between them: e.g. [1-3]; [8-14, 19]; [14-18] They should be organized according to the following forms:

    Article in journal: The reference should include the full last name and initials of the first and middle names of all authors, title of the article, abbreviated title of the journal according to the style used by the PubMed/MEDLINE, year, volume, and inclusive page numbers. Example:

    Kaplan K, Miyamoto R, Levine BR, Egol KA, Zuckerman JD. Surgical management of hip fractures: an evidence-based review of the literature. II: intertrochanteric fractures. J Am Acad Orthop Surg 2008; 16:665-73.

    Chapter in book: The reference should include the full last name and initials of the first and middle names of all authors, title of the chapter, name of the editors, title of the book, place, publisher, year and inclusive page numbers. Example:

    Milford L. Dislocations and ligament us injuries. In: Crenshaw AH (ed): Campbell's operative orthopedics. St. Louis: CV Mosby, 1987, pp. 241-257.

    Book: The reference should include the full last name and initials of the first and middle names of all the authors, title of the book, edition, place, publisher, year and inclusive page numbers. Example:

    Colson JH, Armour WJ. Sports injuries and their treatment. (2nd ed). London: S. Paul, 1986, pp.160-162.

    Web links and URLs: The reference should include the full name of the organization or full last name and initials of the first and middle names of all the authors, title of the web page, year, address, and date of access. Example:

    Turkish Statistical Institute, Turkey Health Survey. 2019 Available from: Accessed: 21 Jan 2020.

    Manuscripts published in electronic format: Example:

    Teasell R, Bhogal SK, Foley N. Painful hemiplegic shoulder. Evidence-Based Review of stroke rehabilitation. 2006 Available from: Evidence-BasedReview-of-Stroke-Rehab.

Main manuscript document should not contain illustrations and figures, and tables. These should be uploaded separately.

Tables should be numbered consecutively in the order of mention in the text. Each table should include a brief title on the same sheet.

Illustrations and figures should be professionally drawn and photographed. All images should be submitted in .JPG and .TIFF formats in 300 Dpi resolutions. The originality of the visual media contained in the reviews should be confirmed by submitting a letter to the journal. The original versions of the printed or electronic copies of the images adapted from a published source should be explicitly cited and the written permission obtained from the copyright holder (publisher, journal or authors) should be forwarded to the journal.