Biochemical Analysis of Bone Related Minerals and Calcium Regulating Hormones in Geriatric Patients With Fracture Due to Minor Trauma

Abstract

Purpose: Biochemical analysis of calcium regulating hormones and bone related minerals in geriatric patients with fracture due to minor trauma.
Patients and methods: 50 patients who were older than 60 years were equally divided into two groups as control and fracture. Fracture group included patients with fracture due to simple fall while on the contrary control group included healthy people at the same age group. Plasma levels of total and ionized calcium, phosphor, magnesium, alkaline phosphatase, calcitonin and parathormon were analyzed. Besides comparison of average plasma values of seven parameters between the control and the fracture groups, comparison of averages between both sex and between different age groups were made. Also, in the fracture group average values at different time intervals after fracture were compared.
Conclusion: It is thought that, in healthy geriatric patients high plasma parathormon levels may be a risk factor for fracture. Plasma calcitonin level rapidly increases after trauma and this causes mobilization of ionized calcium from plasma to bone in early periods of fracture healing. Osteoblastic activity due to fracture decreases with age. Lower plasma levels of calcium in females may be a risk factor for fracture.