Güven Ozan Kaplan1, Fethiye Damla Menkü Özdemir2, Özay Gököz3, Ali Emre Aksu1

1Department of Plastic, Reconstructive and Aesthetic Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey
2Department of Plastic, Reconstructive and Aesthetic Surgery, Karabük Training and Research Hospital, Karabük, Turkey
3Department of Pathology, Hacettepe University Faculty of Medicine, Ankara, Turkey

Keywords: Complex regional pain syndrome, Pacinian corpuscle hyperplasia, neuroma.


Pacinian disorders are exceedingly rare, and the exact pathogenesis is still unknown. The most common symptoms are pain, sensory changes, and a visible or palpable mass, and diagnosis is usually made by pathological examination after the excision of the painful nodule. In this case report, we present the case of a 49-year-old male with Pacinian corpuscle hyperplasia located on the metacarpophalangeal joint, emerging at the same hand of the patient two years after the treatment due to complex regional pain syndrome (CRPS). To the best of our knowledge, this is the first case report revealing the association of CRPS with hyperplasia of Pacinian corpuscles.

Citation: Kaplan GO, Menkü Özdemir FD, Gököz Ö, Aksu AE. First case report of Pacinian corpuscle hyperplasia following complex regional pain syndrome. Jt Dis Relat Surg 2022;33(1):249-252.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.