Comparison of two types of fixation for proximal tibial epiphysiodesis: An experimental study in a rabbit model
Alkan Bayrak1
, Altuğ Duramaz1, Cemal Kızılkaya2, Malik Çelik3, Cemal Kural1, Serdar Altınay4, Alev Kural5, Serdar Hakan Başaran1
1Department of Orthopedics and Traumatology, University of Health Sciences, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
2Department of Orthopedics and Traumatology, Bahçelievler State Hospital, Istanbul, Turkey
3Department of Orthopedics and Traumatology, Batman State Hospital, Batman, Turkey
4Department of Pathology, University of Health Sciences, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
5Department of Biochemistry, University of Health Sciences, Bakırköy Dr. Sadi Konuk Education and Research Hospital, Istanbul, Turkey
Keywords: Eight plate, hemiepiphysiodesis, histology, K-wire, perichondrial ring
Abstract
Objectives: In this study, we describe a novel hemiepiphysiodesis technique to prevent implant-related perichondrial ring injury in a rabbit model.
Materials and methods: Proximal tibial epiphyseal plates of a total of 16 white New Zealand rabbits were used for this animal model. The subjects were divided into three equal groups as follows: Group 1 (Kirschner wire [K-wire]/cerclage), Group 2 (8-plate) right-hind legs, Group 3 (Control) left hind legs. Using anteroposterior radiography, the medial slope angle (MSA), articular line-diaphyseal angle (ALDA), and the angle between screws of 8-plate in lateral X-ray tibial slope angle (TSA) were measured. The radiographs were taken early postoperative (Day 1) and on sacrification day (Week 8). The histological evaluation of the perichondrial ring was made on a 7-mm axial section that stained with Safranin O/fast green at X10 magnification.
Results: In both K-wire and 8-plate groups, the early postoperative ALDA and TSA were greater than the sacrification ALDA and TSA (p=0.028 and p<0.001, respectively). The early postoperative MSA was lower than the sacrification MSA in groups, (p<0.001). The MSA in the control group was lower than the K-wire and 8-plate groups (p<0.001 and p=0.009; respectively). The perichondrial ring thickness of the K-wire group was greater than the 8-plate group in histological evaluation (p<0.001).
Conclusion: Both of the K-wire and 8-plate groups showed similar angulation effects in the proximal tibia, although histologically less damage to the perichondrial ring was observed in the K-wire group, compared to the 8-plate group.
Citation: Bayrak A, Duramaz A, Kızılkaya C, Çelik M, Kural C, Altınay S, et al. Comparison of two types of fixation for proximal tibial epiphysiodesis: An experimental study in a rabbit model. Jt Dis Relat Surg 2021;32(2):468-477.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
Turkish Republic, University of Health Sciences, Scientific Research Projects Unit funds were received in support of this work (2018/010).